Choosing In-Wall Desiccants for Solid Tablets and Capsules (TricorBraun White Papers) (English Edition)

Traditionally solid tablets and capsules sensitive to moisture have been processed under low humidity and packaged in USP tight containers with a separate loose desiccant device (typically silica or clay) inserted in the package. The purpose of this unit-desiccant is to remove the moisture in the headspace of the bottle present at the time of packaging when the heat seal is applied. The degree with which the desiccant can protect the product is limited by the weight of the desiccant, opening size of the bottle or container and its capacity to absorb moisture, as well as the storage conditions for the package. It is not designed for long-term use over the shelf life of the product, and usually not designed to give any protection past the point that the heat seal is broken.