Flavour Science: Chapter 95. Synergistic/Suppressive Effects of Binary and Ternary Mixtures of Sweeteners in Semi-Skimmed Milk

We assessed the sweetness of binary and ternary mixtures of four bulk sweeteners (sucrose, glucose, fructose, and lactose) and seven intense sweeteners (aspartame, acesulfame-K, cyclamate, erythritol, neotame, saccharin, and sucralose) in semi-skimmed milk. The number of synergistic mixtures turned out to be lower than expected (15% of binary mixtures and 3% of ternary mixtures). Suppressive effects, leading up to a 40% reduction in sweetness, were observed in 13% of the binary mixtures and in 5% of the ternary mixtures. No clear trends to predict which ternary mixtures are synergistic on the basis of the binary mixtures were found.