Survey of models for tumor-immune systems dynamics

This unique book is a collection of seven interdisciplinary surveys on modeling tumor dynamics, and interactions between tumors and the immune system. The goal is to provide an accessible, comprehensive report on the field, and to help define a framework for future interdisciplinary research activity. Modeling and simulation of general behaviors of immune systems are also discussed. Each survey carefully covers a specialized field and provides a detailed description of the present state-of-the-art in research. The reader will be able to obtain essential information on the methodological approach used, and on the models that are categorized and used. Taken as a whole, the surveys should provide a complete description of the topic. The first two chapters serve as an interdisciplinary introduction: Chapter One is the view of immunologist, and Chapter Two is that of an applied mathematician. The main features of each survey are put into current context, various models and their related analysis interpretation, and use. Features: A glossary of scientific terms in immunology and biology to insure clear understanding of biological terms A comprehensive and technically accessible overview of relevant models and modeling methods in Chapter Two Simulation techniques and problems presented Topics covered include: general tumor biology modeling, growth kinetics, kinetic cellular theory, tumor-immune system interactions, and heterogeneity and growth control. This book is an excellent resource and survey for applied mathematicians, mathematical biologist and biologists interested in modeling methods in immunology and related sciences. The clear and logical organization, self-contained surveys, and lucid writing styles insure that all professionals, research scientists and graduate students will find the presented material accessible and a helpful guide to the topics. Contents and Contributors: General Aspects of Modelling Immune Response to Tumor Growth/J.A. Adam Mathematical Modelling of Tumor Growth Kinetics/Z. Bajzer, S. Vuk-Pavlovi Tumors Immune System Interactions: The Kinetic Celluar Theory/N. Bellomo, G. Forni Avascular Growth, Angiogenesis and Vascular Growth in Solid Tumors: The Mathematical Modelling of the Stages of Tumor Development/M.A.J. Chaplain Basic Models of Tumor-Immune System Interactions. Identification, Analysis and Predictions/V.A. Kuznetsov Tumor Growth: Growth Factors and Control/S. Michelson, J.T. Leith Series: Modeling and Simulation in Science, Engineering, and Technology